A SOCKS SHOES is the first line of defence for the feet. Socks do a lot more than keep the shoes from rubbing against the feet as well as causing blisters. They help to maintain a comfortable environment by assisting with temperature and moisture management. This type of socks should always be worn by those with neuropathy to assist identify open sores on their feet and ankles. Overall, the first line of defence against blisters is proper sock and shoe fit.